Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil
<strong>Introduction</strong> Synapse loss is the structural correlate of the cognitive decline indicative of dementia. In the brains of Alzheimer's disease sufferers, amyloid β (Aβ) peptides aggregate to form senile plaques but as soluble peptides are toxic to synapses. We previous...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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格式: | Journal article |
語言: | English |
出版: |
Elsevier
2017
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