The role of Wee1 in the hypoxia-induced DNA damage response and its potential as a therapeutic target
<p>The majority of tumours have a poor vasculature which results in low oxygen supply. This, coupled with the high oxygen demand often leads to regions of hypoxia. The physiological relevance of this includes resistance to radiotherapy and chemotherapy, as well as activation of specific signal...
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| Format: | Thesis |
| Language: | English |
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2012
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