Distinct effects of AMPA receptor subunit depletion on spatial memory

Pharmacological studies established a role for AMPARs in the mammalian forebrain in spatial memory performance. Here we generated global GluA1/3 double knockout mice (Gria1/3−/−) and conditional knockouts lacking GluA1 and GluA3 AMPAR subunits specifically from principal cells across the forebrain (...

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Detalles Bibliográficos
Main Authors: Eltokhi, A, Bertocchi, I, Rozov, A, Taylor, A, Rawlins, JNP, Bannerman, DM
Formato: Journal article
Idioma:English
Publicado: Cell Press 2023