Rational development of high-affinity T-cell receptor-like antibodies.

T-cell interaction with a target cell is a key event in the adaptive immune response and primarily driven by T-cell receptor (TCR) recognition of peptide-MHC (pMHC) complexes. TCR avidity for a given pMHC is determined by number of MHC molecules, availability of coreceptors, and TCR affinity for MHC...

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Bibliographic Details
Main Authors:	Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E, Kleber, S, Nuber, N, Stenner-Liewen, F, Bauer, S, McMichael, A, Knuth, A, Abken, H, Cerundolo, V, Jones, E, Renner, C
Format:	Journal article
Language:	English
Published:	2009

Rational development of high-affinity T-cell receptor-like antibodies.

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