New insights into the evolutionary rate of HIV-1 at the within-host and epidemiological levels.
Over calendar time, HIV-1 evolves considerably faster within individuals than it does at the epidemic level. This is a surprising observation since, from basic population genetic theory, we would expect the genetic substitution rate to be similar across different levels of biological organization. T...
主要な著者: | , |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
The Royal Society
2012
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