Meningococcal factor H binding protein fHbpd184 polymorphism influences clinical course of meningococcal meningitis

Factor H Binding protein (fHbp) is an important meningococcal virulence factor, enabling the meningococcus to evade the complement system, and a main target for vaccination. Recently, the structure of fHBP complexed with factor H (fH) was published. Two fHbp glutamic acids, E(283) and E(304), form s...

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Bibliographic Details
Main Authors: Piet, JR, Brouwer, M, Exley, R, Van Der Veen, S, Van De Beek, D, Van Der Ende, A
Format: Journal article
Language:English
Published: Public Library of Science 2012