LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis

Lymphocyte antigen 6 complex, locus E (LY6E) has been implicated in the malignant progression of various types of cancers; however, the underlying mechanism remains unclear. Here, we identified LY6E as an activator of HIF-1 and revealed their mechanistic and functional links in malignant tumor growt...

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Bibliographic Details
Main Authors: Yeom, CJ, Zeng, L, Goto, Y, Morinibu, A, Zhu, Y, Shinomiya, K, Kobayashi, M, Itasaka, S, Yoshimura, M, Hur, C-G, Kakeya, H, Hammond, EM, Hiraoka, M, Harada, H
Format: Journal article
Language:English
Published: Impact Journals 2016