Proteoglycan synthesis in the intervertebral disk nucleus: the role of extracellular osmolality.

Proteoglycans, through their polyelectrolyte properties, regulate the ionic composition and hence the osmotic pressure of the extracellular matrix. We measured the change in [35S]sulfate incorporation, a marker of proteoglycan synthesis, in explants of bovine nucleus pulposus. During incubation, nuc...

Full description

Bibliographic Details
Main Authors: Ishihara, H, Warensjo, K, Roberts, S, Urban, J
Format: Journal article
Language:English
Published: 1997