The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum.

Epidemiological observations suggest that T cell immunity may be suppressed in malaria-endemic areas. In vitro studies, animal models, and limited data in humans link immunosuppression with malaria, malnutrition, and other parasitic infections. However, there are no data to determine whether malaria...

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Bibliographic Details
Main Authors: Bejon, P, Mwacharo, J, Kai, O, Todryk, S, Keating, S, Lowe, B, Lang, T, Mwangi, T, Gilbert, S, Peshu, N, Marsh, K, Hill, A
Format: Journal article
Language:English
Published: 2007