The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers.

RATIONALE: Cognitive impairment is a common feature of depressive illness. While accumulating evidence suggests that brain serotonin (5-HT) pathways play an important role in the neurobiology of depression, the extent to which altered 5-HT function is responsible for the associated changes in cognit...

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Bibliographic Details
Main Authors: Murphy, F, Smith, K, Cowen, P, Robbins, T, Sahakian, B
Format: Journal article
Language:English
Published: 2002