Snapin promotes HIV‐1 transmission from dendritic cells by dampening TLR8 signaling
HIV-1 traffics through dendritic cells (DCs) en route to establishing a productive infection in T lymphocytes but fails to induce an innate immune response. Within DC endosomes, HIV-1 somehow evades detection by the pattern-recognition receptor (PRR) toll-like receptor 8 (TLR8). Using a phosphoprote...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
EMBO Press
2017
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