Resistance of herpes simplex virus type 1 against different phosphonylmethoxyalkyl derivatives of purines and pyrimidines due to specific mutations in the viral DNA polymerase gene.

Míreanna comhchosúla

• Selective abolishment of pyrimidine nucleoside kinase activity of herpes simplex virus type 1 thymidine kinase by mutation of alanine-167 to tyrosine.
  de réir: Degrève, B, et al.
  Foilsithe / Cruthaithe: (2000)
• The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase.
  de réir: Balzarini, J, et al.
  Foilsithe / Cruthaithe: (2002)
• Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.
  de réir: Degrève, B, et al.
  Foilsithe / Cruthaithe: (2001)
• Characterization of multiple nuclear localization signals in herpes simplex virus type 1 thymidine kinase.
  de réir: Degrève, B, et al.
  Foilsithe / Cruthaithe: (1999)
• Detection Of Herpes Simplex Infection In Viral Conjunctivitis Using Polymerase Chain Reaction - A Pilot Study.
  de réir: Ahmad Alwi, Dr. Azma Azalina
  Foilsithe / Cruthaithe: (2004)