[18F]AZD2461, an insight on difference in PARP binding profiles for DNA damage response PET imaging
Purpose Poly(ADP-ribose) polymerase (PARP) inhibitors are extensively studied and used as anti-cancer drugs, as single agents or in combination with other therapies. Most radiotracers developed to date have been chosen on the basis of strong PARP1-3 affinity. Herein, we propose to study AZD2461, a P...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Springer Verlag
2020
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