Effect of glycosphingolipids on osteoclastogenesis and osteolytic bone diseases.
Alterations in glycosphingolipid (GSL) production results in lysosomal storage disorders associated with neurodegenerative changes. In Gaucher's disease, the patients also develop osteoporosis that is ameliorated upon treatment for the underlying defect in GSL metabolism. The role of GSLs in os...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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