Ancestral trees as weighted networks: scalable screening for genome wide association studies

<p>Several haplotype-based methods have been developed to identify loci where multiple mutations of low to moderate frequency and effect size modulate disease susceptibility. Most such approaches either do not scale to hundreds of thousands of genomes or do not explicitly model recombination a...

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Bibliographic Details
Main Author: Christ, R
Other Authors: Aslett, L
Format: Thesis
Published: 2017