Autophagy is activated in systemic lupus erythematosus and required for plasmablast development.

BACKGROUND: Autophagy has emerged as a critical homeostatic mechanism in T lymphocytes, influencing proliferation and differentiation. Autophagy in B cells has been less studied, but genetic deficiency causes impairment of early and late developmental stages OBJECTIVES: To explore the role of autoph...

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Bibliographic Details
Main Authors: Clarke, A, Ellinghaus, U, Cortini, A, Stranks, A, Simon, A, Botto, M, Vyse, T
Format: Journal article
Language:English
Published: 2015