Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice.

Insulin resistance plays a central role in type 2 diabetes and obesity, which develop as a consequence of genetic and environmental factors. Dietary changes including high fat diet (HFD) feeding promotes insulin resistance in rodent models which present useful systems for studying interactions betwe...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Fearnside, J, Dumas, M, Rothwell, A, Wilder, S, Cloarec, O, Toye, A, Blancher, C, Holmes, E, Tatoud, R, Barton, R, Scott, J, Nicholson, J, Gauguier, D
Format: Journal article
Sprache:English
Veröffentlicht: Public Library of Science 2008