Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice.

Insulin resistance plays a central role in type 2 diabetes and obesity, which develop as a consequence of genetic and environmental factors. Dietary changes including high fat diet (HFD) feeding promotes insulin resistance in rodent models which present useful systems for studying interactions betwe...

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Main Authors: Fearnside, J, Dumas, M, Rothwell, A, Wilder, S, Cloarec, O, Toye, A, Blancher, C, Holmes, E, Tatoud, R, Barton, R, Scott, J, Nicholson, J, Gauguier, D
格式: Journal article
語言:English
出版: Public Library of Science 2008