Monitoring poly(ADP-ribosyl)glycohydrolase activity with a continuous fluorescent substrate
The post-translational modification (PTM) and signaling molecule poly(ADP-ribose) (PAR) has an impact on diverse biological processes. This PTM is regulated by a series of ADP-ribosyl glycohydrolases (PARG enzymes) that cleave polymers and/or liberate monomers from their protein targets. Existing me...
| Hauptverfasser: | , , , , |
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| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
Cell Press
2018
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