Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3.

Tumor suppressor p53 regulates the expression of p53-induced genes (PIG) that trigger apoptosis. PIG3 or TP53I3 is the only known member of the medium chain dehydrogenase/reductase superfamily induced by p53 and is used as a proapoptotic marker. Although the participation of PIG3 in the apoptotic pa...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Porté, S, Valencia, E, Yakovtseva, E, Borràs, E, Shafqat, N, Debreczeny, J, Pike, A, Oppermann, U, Farrés, J, Fita, I, Parés, X
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2009