An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus streptomycin + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial

<p><strong>Background</strong></p> <p>Bubonic plague is the primary manifestation of infection with Yersinia pestis, accounting for 90% of all plague cases and with 75% of global cases reported in Madagascar. All drugs in use for treating plague are registered based on...

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Main Authors: Randremanana, RV, Raberahona, M, Randria, MJDD, Rajerison, M, Andrianaivoarimanana, V, Legrand, A, Rasoanaivo, TF, Randriamparany, R, Mayouya-Gamana, T, Mangahasimbola, R, Bourner, J, Salam, A, Gillesen, A, Edwards, T, Schoenhals, M, Baril, L, Horby, P, Olliaro, P
Format: Journal article
Language:English
Published: BioMed Central 2020