Exogenous amino acids are essential for interleukin-7 induced CD8 T cell growth

IL-7 signalling is important in regulating both survival and cellular size (growth) of T cells. While glucose metabolism has previously been implicated in the mechanism of IL-7 induced survival and growth, the role of amino acids has not before been reported. Here, we show IL-7 dependent T cell surv...

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Bibliographic Details
Main Authors: Pearson, C, Silva, A, Seddon, B
Format: Journal article
Language:English
Published: Public Library of Science 2012