NY-ESO-1 protein glycosylated by yeast induces enhanced immune responses.

Vaccine strategies that target dendritic cells to elicit potent cellular immunity are the subject of intense research. Here we report that the genetically engineered yeast Saccharomyces cerevisiae, expressing the full-length tumour-associated antigen NY-ESO-1, is a versatile host for protein product...

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Bibliographic Details
Main Authors: Wadle, A, Mischo, A, Strahl, S, Nishikawa, H, Held, G, Neumann, F, Wullner, B, Fischer, E, Kleber, S, Karbach, J, Jager, E, Shiku, H, Odunsi, K, Shrikant, P, Knuth, A, Cerundolo, V, Renner, C
Format: Journal article
Language:English
Published: 2010