Structure of the MlaC-MlaD complex reveals molecular basis of periplasmic phospholipid transport

The Maintenance of Lipid Asymmetry (Mla) pathway is a multicomponent system found in all gram-negative bacteria that contributes to virulence, vesicle blebbing and preservation of the outer membrane barrier function. It acts by removing ectopic lipids from the outer leaflet of the outer membrane and...

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Bibliographic Details
Main Authors: Wotherspoon, P, Johnston, H, Hardy, DJ, Holyfield, R, Bui, S, Ratkevičiūtė, G, Sridhar, P, Colburn, J, Wilson, CB, Colyer, A, Cooper, BF, Bryant, JA, Hughes, GW, Stansfeld, PJ, Bergeron, JRC, Knowles, TJ
Format: Journal article
Language:English
Published: Nature Research 2024