-(S)-Alpha-phenyl-2-pyridine-ethanamine Dihydrochloride-, a low affinity uncompetitive N-methyl-D-aspartic acid antagonist, is effective in rodent models of global and focal ischemia.

-(S)-Alpha-phenyl-2-pyridine-ethanamine Dihydrochloride-, a low affinity uncompetitive N-methyl-D-aspartic acid antagonist, is effective in rodent models of global and focal ischemia.

[(S)-Alpha-phenyl-2-pyridine-ethanamine dihydrochloride] (ARL 15896AR) is a low affinity uncompetitive N-methyl-D-aspartic acid receptor antagonist that was tested in animal models of anoxia and ischemia. Pretreatment of rodents with ARL 15896AR extended survival time during exposure to hypoxia. Wit...

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Bibliographic Details
Main Authors: Cregan, E, Peeling, J, Corbett, D, Buchan, A, Saunders, J, Auer, R, Gao, M, Mccarthy, D, Eisman, MS, Campbell, T, Murray, R, Stagnitto, M, Palmer, G
Format: Journal article
Language:English
Published: 1997

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