-(S)-Alpha-phenyl-2-pyridine-ethanamine Dihydrochloride-, a low affinity uncompetitive N-methyl-D-aspartic acid antagonist, is effective in rodent models of global and focal ischemia.
[(S)-Alpha-phenyl-2-pyridine-ethanamine dihydrochloride] (ARL 15896AR) is a low affinity uncompetitive N-methyl-D-aspartic acid receptor antagonist that was tested in animal models of anoxia and ischemia. Pretreatment of rodents with ARL 15896AR extended survival time during exposure to hypoxia. Wit...
Main Authors: | Cregan, E, Peeling, J, Corbett, D, Buchan, A, Saunders, J, Auer, R, Gao, M, Mccarthy, D, Eisman, MS, Campbell, T, Murray, R, Stagnitto, M, Palmer, G |
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Format: | Journal article |
Language: | English |
Published: |
1997
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