Promoter type influences transcriptional topography by targeting genes to distinct nucleoplasmic sites.
Both the sequence of a promoter and the position of a gene in 3D nuclear space play crucial roles in gene regulation, but few studies address their inter-relationship. Using human and viral promoters on mini-chromosomes and RNA fluorescence in situ hybridization coupled to 'high-precision'...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2013
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