Promoter type influences transcriptional topography by targeting genes to distinct nucleoplasmic sites.

Both the sequence of a promoter and the position of a gene in 3D nuclear space play crucial roles in gene regulation, but few studies address their inter-relationship. Using human and viral promoters on mini-chromosomes and RNA fluorescence in situ hybridization coupled to 'high-precision'...

Descrizione completa

Dettagli Bibliografici
Autori principali: Larkin, J, Papantonis, A, Cook, P
Natura: Journal article
Lingua:English
Pubblicazione: 2013