Promoter type influences transcriptional topography by targeting genes to distinct nucleoplasmic sites.

Both the sequence of a promoter and the position of a gene in 3D nuclear space play crucial roles in gene regulation, but few studies address their inter-relationship. Using human and viral promoters on mini-chromosomes and RNA fluorescence in situ hybridization coupled to 'high-precision'...

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Main Authors: Larkin, J, Papantonis, A, Cook, P
格式: Journal article
语言:English
出版: 2013