A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila.

Active zones (AZs) are presynaptic membrane domains mediating synaptic vesicle fusion opposite postsynaptic densities (PSDs). At the Drosophila neuromuscular junction, the ELKS family member Bruchpilot (BRP) is essential for dense body formation and functional maturation of AZs. Using a proteomics a...

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Bibliographic Details
Main Authors: Owald, D, Fouquet, W, Schmidt, M, Wichmann, C, Mertel, S, Depner, H, Christiansen, F, Zube, C, Quentin, C, Körner, J, Urlaub, H, Mechtler, K, Sigrist, S
Format: Journal article
Language:English
Published: 2010