Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy.

In recent years, oligonucleotide-based molecules have been intensely used to modulate gene expression. All these molecules share the common feature of being essentially impermeable over cellular membranes and they therefore require efficient delivery vectors. Cell-penetrating peptides are a group of...

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Bibliographic Details
Main Authors: Lehto, T, Abes, R, Oskolkov, N, Suhorutsenko, J, Copolovici, D, Mäger, I, Viola, JR, Simonson, O, Ezzat, K, Guterstam, P, Eriste, E, Smith, C, Lebleu, B, Samir El Andaloussi, Langel, U
Format: Journal article
Language:English
Published: 2010