2'-Alkynylnucleotides: A Sequence- and Spin Label-Flexible Strategy for EPR Spectroscopy in DNA

Electron paramagnetic resonance (EPR) spectroscopy is a powerful method to elucidate molecular structure through the measurement of distances between conformationally well-defined spin labels. Here we report a sequence-flexible approach to the synthesis of double spin-labeled DNA duplexes, where 2′-...

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Bibliographic Details
Main Authors: Anderson, E, El-Sagheer, A, Porter, R, Brown, T, Haugland, M, Peña, J, Lovett, J
Format: Journal article
Published: American Chemical Society 2016