Pan-genomic binding of hypoxia-inducible transcription factors.

Hypoxia-inducible transcription factors (HIFs) mediate the cellular response to hypoxia. HIF-DNA binding triggers a transcriptional program that acts to both restore oxygen homeostasis and adapt cells to low oxygen availability. In this context, HIF is centrally involved in many physiologic and path...

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Bibliographic Details
Main Authors: Schödel, J, Mole, D, Ratcliffe, P
Format: Journal article
Language:English
Published: 2013