Pan-genomic binding of hypoxia-inducible transcription factors.
Hypoxia-inducible transcription factors (HIFs) mediate the cellular response to hypoxia. HIF-DNA binding triggers a transcriptional program that acts to both restore oxygen homeostasis and adapt cells to low oxygen availability. In this context, HIF is centrally involved in many physiologic and path...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2013
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