Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage

Hematopoietic stem cells (HSCs) that sustain lifelong blood production are created during embryogenesis. They emerge from a specialized endothelial population, termed hemogenic endothelium (HE), located in the ventral wall of the dorsal aorta (DA). In Xenopus, we have been studying the gene regulato...

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Bibliografski detalji
Glavni autori: Kirmizitas, A, Meiklejohn, S, Ciau-Uitz, A, Stephenson, R, Patient, R
Format: Journal article
Jezik:English
Izdano: Proceedings of the National Academy of Sciences 2017