Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage

Hematopoietic stem cells (HSCs) that sustain lifelong blood production are created during embryogenesis. They emerge from a specialized endothelial population, termed hemogenic endothelium (HE), located in the ventral wall of the dorsal aorta (DA). In Xenopus, we have been studying the gene regulato...

Full description

Bibliographic Details
Main Authors: Kirmizitas, A, Meiklejohn, S, Ciau-Uitz, A, Stephenson, R, Patient, R
Format: Journal article
Language:English
Published: Proceedings of the National Academy of Sciences 2017