Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage
Hematopoietic stem cells (HSCs) that sustain lifelong blood production are created during embryogenesis. They emerge from a specialized endothelial population, termed hemogenic endothelium (HE), located in the ventral wall of the dorsal aorta (DA). In Xenopus, we have been studying the gene regulato...
Main Authors: | Kirmizitas, A, Meiklejohn, S, Ciau-Uitz, A, Stephenson, R, Patient, R |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Proceedings of the National Academy of Sciences
2017
|
Similar Items
-
VEGFA-dependent and -independent pathways synergise to drive Scl expression and initiate programming of the blood stem cell lineage in Xenopus.
by: Ciau-Uitz, A, et al.
Published: (2013) -
Notch input to blood stem cell programming during Xenopus ontogeny
by: Stephenson, R, et al.
Published: (2011) -
Gene regulatory networks governing the generation and regeneration of blood
by: Ciau-Uitz, A, et al.
Published: (2019) -
Adult and embryonic blood and endothelium derive from distinct precursor populations which are differentially programmed by BMP in Xenopus.
by: Walmsley, M, et al.
Published: (2002) -
Developmental hematopoiesis: ontogeny, genetic programming and conservation.
by: Ciau-Uitz, A, et al.
Published: (2014)