Remodelling of the immune landscape and its effect of tumour immunity in a model of IFNy-insensitive murine melanoma
<p>Loss of IFNγ-sensitivity by tumour cells appears to enable evasion against T cell-dependent cytotoxicity, as some cancers lacking IFNγ-signalling demonstrate clinical resistance to checkpoint immunotherapy. However, recent studies have demonstrated that IFNγ-resistant tumours can sensitize...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
2023
|
| Subjects: |