Artemether-lumefantrine to treat malaria in pregnancy is associated with reduced placental haemozoin deposition compared to quinine in a randomized controlled trial.

BACKGROUND: Data on efficacy of artemisinin-based combination therapy (ACT) to treat Plasmodium falciparum during pregnancy in sub-Saharan Africa is scarce. A recent open label, randomized controlled trial in Mbarara, Uganda demonstrated that artemether-lumefantrine (AL) is not inferior to quinine t...

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Bibliographic Details
Main Authors: Muehlenbachs, A, Nabasumba, C, McGready, R, Turyakira, E, Tumwebaze, B, Dhorda, M, Nyehangane, D, Nalusaji, A, Nosten, F, Guerin, P, Piola, P
Format: Journal article
Language:English
Published: BioMed Central 2012