Dendritic cells process exogenous viral proteins and virus-like particles for class I presentation to CD8+ cytotoxic T lymphocytes.

Previous reports have indicated that both dendritic cells and macrophages have the ability to induce cytotoxic T lymphocyte (CTL) and T helper (Th) cell responses in vivo. Dendritic cells process exogenous antigens conventionally for presentation on major histocompatibility complex (MHC) class II mo...

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Bibliographic Details
Main Authors: Bachmann, M, Lutz, M, Layton, G, Harris, S, Fehr, T, Rescigno, M, Ricciardi-Castagnoli, P
Format: Journal article
Language:English
Published: 1996