Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations

It is important to study the genetics of complex traits in diverse populations. Here, we introduce covariate-adjusted linkage disequilibrium (LD) score regression (cov-LDSC), a method to estimate SNP-heritability (h2 g) and its enrichment in homogenous and admixed populations with summary statistics...

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Bibliographic Details
Main Authors: Luo, YL, Li, X, Wang, X, Raychaudhuri, R
Format: Journal article
Language:English
Published: Oxford University Press 2021