The impact of trisomy 21 on early human hematopoiesis.
Although children with Down syndrome (DS) are not cancer-prone in general, they have a 150-fold increased risk of acute myeloid leukemia of DS (ML-DS) and a 33-fold increased risk of B-cell acute lymphoblastic leukemia (B-ALL). In virtually all cases of ML-DS, but not in other leukemias, the leukemi...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Taylor and Francis
2013
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