Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity.
The 5' flanking region of the human alpha-globin gene is highly G + C rich and contains multiple copies of the consensus sequence for the Sp1 binding site. We investigated the role of this G + C-rich region in augmenting alpha-globin promoter activity in the presence of the far-upstream alpha-g...
Váldodahkkit: | , , , , |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
1995
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