Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity.

The 5' flanking region of the human alpha-globin gene is highly G + C rich and contains multiple copies of the consensus sequence for the Sp1 binding site. We investigated the role of this G + C-rich region in augmenting alpha-globin promoter activity in the presence of the far-upstream alpha-g...

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Váldodahkkit: Pondel, MD, Murphy, S, Pearson, L, Craddock, C, Proudfoot, N
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 1995