Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.
Chronic infections strain the regenerative capacity of antiviral T lymphocyte populations, leading to failure in long-term immunity. The cellular and molecular events controlling this regenerative capacity, however, are unknown. We found that two distinct states of virus-specific CD8(+) T cells exis...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Association for the Advancement of Science
2012
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