K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration.

Phasic activation of the dopamine (DA) midbrain system in response to unexpected reward or novelty is critical for adaptive behavioral strategies. This activation of DA midbrain neurons occurs via a synaptically triggered switch from low-frequency background spiking to transient high-frequency burst...

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Bibliographic Details
Main Authors: Schiemann, J, Schlaudraff, F, Klose, V, Bingmer, M, Seino, S, Magill, P, Zaghloul, K, Schneider, G, Liss, B, Roeper, J
Format: Journal article
Language:English
Published: 2012