Activation of endocytosis as an adaptation to the mammalian host by trypanosomes.

Activation of endocytosis as an adaptation to the mammalian host by trypanosomes.

Immune evasion in African trypanosomes is principally mediated by antigenic variation, but rapid internalization of surface-bound immune factors may contribute to survival. Endocytosis is upregulated approximately 10-fold in bloodstream compared to procyclic forms, and surface coat remodeling accomp...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Natesan, S, Peacock, L, Matthews, K, Gibson, W, Field, M
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2007

Eitemau Tebyg

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High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.
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