Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells and in a small cell lung cancer cell line

It is well established that chromosomes exist in discrete territories (CTs) in interphase and are positioned in a cell-type specific probabilistic manner. The relative localisation of individual CTs within cell nuclei remains poorly understood, yet many cancers are associated with specific chromosom...

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Bibliographic Details
Main Authors: Themis, M, Garimberti, E, Estrada, G, Arsuaga, J, Hill, M, Bridger, J, Anderson, R
Format: Journal article
Published: 2012