Significance of Na/Ca exchange for Ca2+ buffering and electrical activity in mouse pancreatic beta-cells.

Significance of Na/Ca exchange for Ca2+ buffering and electrical activity in mouse pancreatic beta-cells.

We have combined the patch-clamp technique with microfluorimetry of the cytoplasmic Ca2+ concentration ([Ca2+]i) to characterize Na/Ca exchange in mouse beta-cells and to determine its importance for [Ca2+]i buffering and shaping of glucose-induced electrical activity. The exchanger contributes to C...

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Autors principals:	Gall, D, Gromada, J, Susa, I, Rorsman, P, Herchuelz, A, Bokvist, K
Format:	Journal article
Idioma:	English
Publicat:	1999

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