Significance of Na/Ca exchange for Ca2+ buffering and electrical activity in mouse pancreatic beta-cells.

Significance of Na/Ca exchange for Ca2+ buffering and electrical activity in mouse pancreatic beta-cells.

We have combined the patch-clamp technique with microfluorimetry of the cytoplasmic Ca2+ concentration ([Ca2+]i) to characterize Na/Ca exchange in mouse beta-cells and to determine its importance for [Ca2+]i buffering and shaping of glucose-induced electrical activity. The exchanger contributes to C...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Gall, D, Gromada, J, Susa, I, Rorsman, P, Herchuelz, A, Bokvist, K
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	1999

Παρόμοια τεκμήρια

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ανά: Gall, D, κ.ά.
Έκδοση: (1996)

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ανά: Gall, D, κ.ά.
Έκδοση: (1997)

THE IMPORTANCE OF NA/CA-EXCHANGE IN RESTORING RESTING CYTOSOLIC CALCIUM LEVELS IN MOUSE BETA-CELLS
ανά: Bokvist, K, κ.ά.
Έκδοση: (1995)

LOCAL INTRACELLULAR CA2+-GRADIENTS ASSOCIATED WITH CA2+ ENTRY INTO AND SECRETION FROM MOUSE PANCREATIC BETA-CELLS
ανά: Bokvist, K, κ.ά.
Έκδοση: (1993)

Role of Na/Ca exchange and the plasma membrane Ca2+-ATPase in cell function. Conference on Na/Ca exchange.
ανά: Noble, D, κ.ά.
Έκδοση: (2007)

Block of ATP-regulated and Ca2(+)-activated K+ channels in mouse pancreatic beta-cells by external tetraethylammonium and quinine.
ανά: Bokvist, K, κ.ά.
Έκδοση: (1990)

Compound exocytosis in voltage-clamped mouse pancreatic beta-cells revealed by carbon fibre amperometry.
ανά: Bokvist, K, κ.ά.
Έκδοση: (2000)

CaM kinase II-dependent mobilization of secretory granules underlies acetylcholine-induced stimulation of exocytosis in mouse pancreatic B-cells.
ανά: Gromada, J, κ.ά.
Έκδοση: (1999)

Adrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels.
ανά: Gromada, J, κ.ά.
Έκδοση: (1997)

Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells.
ανά: Bokvist, K, κ.ά.
Έκδοση: (1995)

Acetylcholine inhibits voltage-dependent Ca2+ channels in mouse pancreatic B-cells.
ανά: Gilon, P, κ.ά.
Έκδοση: (1996)

Dual effects of glucose on the cytosolic Ca2+ activity of mouse pancreatic beta-cells.
ανά: Rorsman, P, κ.ά.
Έκδοση: (1984)

Modulation of dihydropyridine-sensitive Ca2+ channels by glucose metabolism in mouse pancreatic beta-cells.
ανά: Smith, P, κ.ά.
Έκδοση: (1989)

Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.
ανά: Høy, M, κ.ά.
Έκδοση: (2003)

Delayed rectifying and calcium-activated K+ channels and their significance for action potential repolarization in mouse pancreatic beta-cells.
ανά: Smith, P, κ.ά.
Έκδοση: (1990)

G protein-dependent inhibition of L-type Ca2+ currents by acetylcholine in mouse pancreatic B-cells.
ανά: Gilon, P, κ.ά.
Έκδοση: (1997)

Effects of external tetraethylammonium ions and quinine on delayed rectifying K+ channels in mouse pancreatic beta-cells.
ανά: Bokvist, K, κ.ά.
Έκδοση: (1990)

Calcium and pancreatic beta-cell function. XI. Modification of 45Ca fluxes by Na+ removal.
ανά: Hellman, B, κ.ά.
Έκδοση: (1980)

Single Ca channel currents in mouse pancreatic B-cells.
ανά: Rorsman, P, κ.ά.
Έκδοση: (1988)

DIRECT EVIDENCE THAT GLUCOSE BOTH REDUCES AND INCREASES CYTOSOLIC FREE CA-2+ IN MOUSE PANCREATIC BETA-CELLS
ανά: Rorsman, P, κ.ά.
Έκδοση: (1984)

Direct measurements of increased free cytoplasmic Ca2+ in mouse pancreatic beta-cells following stimulation by hypoglycemic sulfonylureas.
ανά: Abrahamsson, H, κ.ά.
Έκδοση: (1985)

Inositol trisphosphate-dependent periodic activation of a Ca(2+)-activated K+ conductance in glucose-stimulated pancreatic beta-cells.
ανά: Ammälä, C, κ.ά.
Έκδοση: (1991)

Adrenaline stimulates secretion in rat pancreatic alpha-cells by PKA-dependent acceleration of Ca2+ influx through 1-type Ca2+- channels
ανά: Gromada, J, κ.ά.
Έκδοση: (1996)

Ca(2+)- and GTP-dependent exocytosis in mouse pancreatic beta-cells involves both common and distinct steps.
ανά: Proks, P, κ.ά.
Έκδοση: (1996)

Inhibition of ATP-regulated K(+)-channels by a photoactivatable ATP-analogue in mouse pancreatic beta-cells.
ανά: Ammälä, C, κ.ά.
Έκδοση: (1991)

DIRECT EVIDENCE FOR THE EXISTENCE OF HOT-SPOTS OF SECRETION IN MOUSE PANCREATIC BETA-CELLS
ανά: Bokvist, K, κ.ά.
Έκδοση: (1994)

Inhibition of L-type calcium channels by internal GTP [gamma S] in mouse pancreatic beta cells.
ανά: Ammälä, C, κ.ά.
Έκδοση: (1992)

MOLECULAR MECHANISM BEHIND DESENSITIZATION OF GLP-1(7-36)AMIDE-EVOKED CA2+ RELEASE FROM INTERNAL STORES IN BETA-TC3 CELLS
ανά: Gromada, J, κ.ά.
Έκδοση: (1995)

Acetylcholine stimulates exocytosis by acceleration of granula mobilisation in mouse pancreatic B-cells
ανά: Gromada, J, κ.ά.
Έκδοση: (1998)

Activation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells.
ανά: Göpel, S, κ.ά.
Έκδοση: (1999)

Activation of Ca2+-dependent K+ channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells
ανά: Gopel, S, κ.ά.
Έκδοση: (1999)

Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells.
ανά: Olofsson, C, κ.ά.
Έκδοση: (2004)

A NOVEL LOW-CONDUCTANCE K+-CHANNEL PRODUCING MEMBRANE-POTENTIAL OSCILLATIONS IN MOUSE PANCREATIC BETA-CELLS
ανά: Bokvist, K, κ.ά.
Έκδοση: (1992)

Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells.
ανά: Larsson, O, κ.ά.
Έκδοση: (1993)

The Na+/Ca2+ exchanger NCX3 mediates Ca2+ entry into matrix vesicles to facilitate initial steps of mineralization in osteoblasts
ανά: Irshad A. Sheikh, κ.ά.
Έκδοση: (2024-06-01)

CA-INDEPENDENT STIMULATION OF EXOCYTOSIS BY GTP IN SINGLE-MOUSE PANCREATIC BETA-CELLS
ανά: Proks, P, κ.ά.
Έκδοση: (1994)

Alpha 2-adrenoreceptor stimulation does not inhibit L-type calcium channels in mouse pancreatic beta-cells.
ανά: Bokvist, K, κ.ά.
Έκδοση: (1991)

Fast exocytosis by Ca2+-channel-granule interaction in mouse pancreatic B-cells
ανά: Renstrom, E, κ.ά.
Έκδοση: (1999)

Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling.
ανά: Gromada, J, κ.ά.
Έκδοση: (1998)

Modelling of electrical activity in pancreatic islets: The role of a novel K-Ca-channel.
ανά: Galvanovskis, J, κ.ά.
Έκδοση: (2000)