Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without beta-propiolactone, in the treatment of Bothrops asper bites in Colombia.

The efficacy and safety of two whole IgG polyvalent antivenoms (A and B) were compared in a randomised, blinded clinical trial in 67 patients systemically envenomed by Bothrops asper in Colombia. Both antivenoms were fractionated by caprylic acid precipitation and had similar neutralising potencies,...

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Bibliographic Details
Main Authors: Otero, R, León, G, Gutiérrez, J, Rojas, G, Toro, M, Barona, J, Rodríguez, V, Díaz, A, Núñez, V, Quintana, J, Ayala, S, Mosquera, D, Conrado, L, Fernández, D, Arroyo, Y, Paniagua, C, López, M, Ospina, C, Alzate, C, Fernández, J, Meza, J, Silva, J, Ramírez, P, Fabra, P, Ramírez, E
Format: Journal article
Language:English
Published: 2006