The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis.
The epicardium, the outermost tissue layer that envelops the developing heart and provides essential trophic signals for the myocardium, derives from the pro-epicardial organ (PEO). Two of the three members of the Flrt family of transmembrane glycoproteins, Flrt2 and Flrt3, are strongly co-expressed...
Main Authors: | Müller, P, Schulz, R, Maretto, S, Costello, I, Srinivas, S, Bikoff, E, Robertson, E |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
2011
|
Registos relacionados
-
Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3.
Por: Maretto, S, et al.
Publicado em: (2008) -
Epigenetically regulated Fibronectin leucine rich transmembrane protein 2 (FLRT2) shows tumor suppressor activity in breast cancer cells
Por: Hansol Bae, et al.
Publicado em: (2017-03-01) -
Expression, refolding and spectroscopic characterization of fibronectin type III (FnIII)-homology domains derived from human fibronectin leucine rich transmembrane protein (FLRT)-1, -2, and -3
Por: Lila Yang, et al.
Publicado em: (2017-07-01) -
A conserved gene family encodes transmembrane proteins with fibronectin, immunoglobulin and leucine-rich repeat domains (FIGLER)
Por: Haga Christopher L, et al.
Publicado em: (2007-09-01) -
A protocadherin-cadherin-FLRT3 complex controls cell adhesion and morphogenesis.
Por: Xuejun Chen, et al.
Publicado em: (2009-12-01)