Interplay of the osmotic environment and a fibronectin fragment in intervertebral disc cell metabolism
<p>Breakdown of the disc extracellular matrix is thought to arise from increased activity of matrix metalloproteinases (MMPs). Aggrecan, one of the major disc matrix macromolecules, is degraded through action of MMPs and aggrecanases and its concentration falls early in the degeneration proces...
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Format: | Thesis |
Language: | English |
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2011
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